Xiaoyue Sun

ORCID: 0000-0001-8167-3108 · 2 papers in corpus

other 2026

Dose-Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced science (Weinheim, Baden-Wurttemberg, Germany) ·doi:10.1002/advs.202521702

Iron overload induces cellular stress and is implicated in diverse pathological conditions. Nevertheless, the epigenetic mechanisms governing mammalian cellular responses to iron overload remain poorly characterized. Using multi-omics profi…

article 2024

Comparison of chromatin accessibility remodeling of granulosa cells in patients with endometrioma or pelvic/tubal infertility

Journal of assisted reproduction and genetics ·doi:10.1007/s10815-024-03302-7

PURPOSE: To elucidatethe epigenetic alteration associated with impaired oogenesis in endometrioma using multi-omic approaches. METHODS: ATAC-seq was performed on the granulosa cells (GCs) of 6 patients (3 with endometrioma and 3 without). …