Terhi Piltonen

ORCID: 0000-0002-9921-7300 · 35 papers in corpus
other 2017
Biology of reproduction ·doi:10.1093/biolre/iox092

Human endometrium undergoes extensive regeneration on a cyclic basis in premenopausal women and likely occurs through the contribution of stem/progenitor cells. Menopause results in the permanent cessation of menstrual cycles and is precede…

lab-animal 2016
Biology of reproduction ·doi:10.1095/biolreprod.115.136010

Human endometrium undergoes cyclic regeneration involving stem/progenitor cells, but the role of resident endometrial mesenchymal stem cells (eMSC) as progenitors of endometrial stromal fibroblasts (eSF) has not been definitively demonstrat…

review 2016
Best practice & research. Clinical obstetrics & gynaecology ·doi:10.1016/j.bpobgyn.2016.03.008

Women with polycystic ovarian syndrome (PCOS) present with several endometrial abnormalities possibly explaining some of the adverse endometrium-related outcomes in these women. PCOS and an increased miscarriage rate have been suggested to …

observational 2016
Human reproduction (Oxford, England) ·doi:10.1093/humrep/dew249

STUDY QUESTION: Are uterine fibroids associated with increased cardiovascular risk? SUMMARY ANSWER: This study reports an association between increased serum lipids and metabolic syndrome with an increased risk of uterine fibroids. WHAT I…

2015
lab-animal 2015
Human reproduction (Oxford, England) ·doi:10.1093/humrep/dev055

STUDY QUESTION: Do endometrial stromal fibroblasts (eSF) in women with polycystic ovary syndrome (PCOS) (eSFpcos) exhibit altered estrogen and/or progesterone (P4) responses, which may explain some of the adverse reproductive outcomes and e…

lab-animal 2014
·doi:10.5301/je.5000198

Purpose Decidualization comprises specific biochemical and morphological changes in uterine endometrium essential for establishment of pregnancy. This process is abnormal in women with endometriosis, a disorder in which endometrial-like tis…

lab-animal 2013
Fertility and sterility ·doi:10.1016/j.fertnstert.2013.06.007

OBJECTIVE: To determine the effects of coculturing endometrial epithelial cells (eEC) with paired endometrial stromal fibroblasts (eSF) on cell-specific gene expression and cytokine secretion patterns. DESIGN: In vitro study. SETTING: Uni…

other 2013
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2013-1923

CONTEXT: Endometrium in polycystic ovary syndrome (PCOS) presents altered gene expression indicating progesterone resistance and predisposing to reduced endometrial receptivity and endometrial cancer. OBJECTIVE: We hypothesized that an alt…

2007
·doi:10.1093/humrep/dem1068

Conclusions:The size of the 2 -5 mm follicle pool is an independent and important contributor to the FA of PCOS.This result could be explained by an exaggerated physiological inhibitory effect from this pool on the terminal follicle growth,…