Srividya Seshadri

PurposeOocyte quality declines with age and metabolic stress, largely due to mitochondrial dysfunction and NAD⁺ depletion. Nicotinamide mononucleotide (NMN), a precursor of NAD⁺, has emerged as a potential intervention to restore cellular e…

There are no conflicts of interest.

Endometriosis is a chronic inflammatory condition in women of reproductive age, which can lead to infertility and pelvic pain. Endometriosis associated infertility is multifactorial in nature adversely affecting each step of the natural rep…

PurposeUtilising non-invasive imaging parameters to assess human oocyte fertilisation, development and implantation; and their influence on transcriptomic profiles.MethodsA ranking tool was designed using imaging data from 957 metaphase II …

BackgroundThe advent of ovarian stimulation within an in vitro fertilization (IVF) cycle has resulted in modifying the physiology of stimulated cycles and has helped optimize pregnancy outcomes. In this regard, the importance of progesteron…

PurposeTo compare in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) in regard to post-fertilization development and outcome with the purpose of ascertaining the most effective fertilization method for assisted reprod…

BackgroundScreening hysteroscopy in infertile women with unexplained infertility, or prior to intrauterine insemination (IUI) or in vitro fertilisation (IVF) may reveal intrauterine pathology that may not be detected by routine transvaginal…

Demands on the gynaecologist from patients seeking help with suboptimal fertility continue to grow, and fertility-related issues are often in the gaze of the media. Obstetricians and gynaecologists need to ensure that they are up to date, i…

Background: Various gynecologic pathologies affect in-vitro fertilization (IVF) treatment detrimentally. Timely management of these pathologies could improve IVF outcomes. However, there is a lack of evidence-based guidelines on the appropr…