Mostafa M Hamed

No ORCID on file · 1 paper in corpus · active 2019

Study types

  • other 1

Condition tags

  • endometriosis 1
other 2019
Development of potential preclinical candidates with promising in vitro ADME profile for the inhibition of type 1 and type 2 17β-Hydroxysteroid dehydrogenases: Design, synthesis, and biological evaluation
European journal of medicinal chemistry ·doi:10.1016/j.ejmech.2019.05.084

Estrogens are the major female sex steroid hormones, estradiol (E2) being the most potent form in humans. Disturbing the balance between E2 and its weakly active oxidized form estrone (E1) leads to diverse types of estrogen-dependent diseas…