Ting‐Tai Yen — Endo Lab

article 2026

GLP-1 Receptor Agonists Plus Progestins and Endometrial Cancer Risk in Nonmalignant Uterine Diseases

·doi:10.1001/jamanetworkopen.2025.58205

Importance: As endometrial cancer (EC) incidence rises, particularly among individuals with obesity and metabolic disorders, effective strategies targeting hormonal and metabolic risks are needed. Objective: To evaluate EC risk in patients …

article 2025

Effects of glucagon-like peptide-1 receptor agonists on incident gynecologic cancer outcomes in endometriosis patients compared to metformin: A real-world multicenter retrospective cohort study across the United States

·doi:10.1016/j.ygyno.2025.04.222

2018

Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers.

Science translational medicine ·doi:10.1126/scitranslmed.aap8793

We report the detection of endometrial and ovarian cancers based on genetic analyses of DNA recovered from the fluids obtained during a routine Papanicolaou (Pap) test. The new test, called PapSEEK, incorporates assays for mutations in 18 g…

2018

Methylomic Analysis of Ovarian Cancers Identifies Tumor-Specific Alterations Readily Detectable in Early Precursor Lesions.

Clinical cancer research : an official journal of the American Association for Cancer Research ·doi:10.1158/1078-0432.ccr-18-1199

PurposeHigh-grade serous ovarian carcinoma (HGSOC) typically remains undiagnosed until advanced stages when peritoneal dissemination has already occurred. Here, we sought to identify HGSOC-specific alterations in DNA methylation and assess …