Lin Y

BACKGROUND: Uterine prolapse (UP), a subtype of pelvic organ prolapse (POP), frequently coexists with urinary tract infections (UTIs) and lower urinary tract symptoms (LUTS), including urinary frequency (UF), urinary incontinence (UI), and …

Abstract Objective This study evaluates the potential of complement C3 as a predictive biomarker for endometriosis severity and examines its correlation with clinical features and biochemical markers. Methods In this retrospective analys…

High incidence of unexplained miscarriage (UM) limits global human reproduction. Lithium (Li) batteries are widely used but rarely recycled, causing Li to spread into environments and enter human body. Notably, the healthy effects of Li exp…

Endometriosis, a gynecological disorder marked by pelvic pain and infertility, has its pathogenesis and pathophysiology significantly influenced by epigenetics, as these factors have been well characterized. However, the role of RNA-mediate…

The significance of multi-combination machine learning models utilizing vision transformer (VIT) features in forecasting pathological complete response (pCR) after breast cancer neoadjuvant therapy (NAT). A retrospective study was conducted…

Non-invasive prenatal testing (NIPT) not only enables the detection of chromosomal anomalies in fetuses but also generates vast amounts of ultra-low-depth sequencing data, which can be leveraged for population genomic studies. Here, we pres…

BACKGROUND: Pelvic abscesses represent acute gynecological emergencies requiring timely intervention. This study evaluated prognostic predictors and treatment modalities in patients with pelvic abscesses. METHODS: We conducted a retrospect…

Endometriosis is a common gynecological disease that causes severe pain and infertility. However, the available treatments for EMS are limited. SCM-198, a synthetic form of leonurine, possesses various abilities, including anti-inflammatory…

BACKGROUND: Intramural pregnancy (IMP) is a subtype of ectopic pregnancy that can lead to life-threatening uterine rupture and severe hemorrhage. However, the clinical manifestations of IMP are nonspecific, making early clinical recognition…

INTRODUCTION: Adenomyosis is a prevalent gynaecological disorder affecting women of reproductive age, yet the underlying etiology and cellular-molecular mechanisms driving its pathogenesis remain poorly understood. Gonadotropin-releasing ho…

Abstract Adenomyosis is a prevalent and non-cancerous uterine disease which can significantly impaired the fertility of reproductive-age women. However, the etiology, as well as the cellular and molecular mechanism underlying adenomyosis re…

Endometriosis significantly impacts the physical and mental health of women of reproductive age. While some patients can achieve pregnancy through surgery or in vitro fertilization (IVF), many still struggle with IVF failure due to poor ooc…

OBJECTIVE: To investigate the impact of changes in luteinizing hormone (LH) levels during ovulation induction using flexible gonadotropin-releasing hormone antagonist (GnRH-A) regimens in POSEIDON groups 1 and 2 on the clinical outcomes of …

m6A regulators were demonstrated to modulate the functions of intestinal epithelial and immune cells in the ulcerative colitis. This study aimed to elucidate whether and how the m6A reader heterogeneous nuclear ribonucleoprotein C (HNRNPC) …

Abstract Background Patients with adenomyosis are thought to exist in a hypercoagulable state; however, the specific alterations in thromboelastography (TEG) remain to be elucidated. This study aimed to assess changes in TEG metrics and t…

RATIONALE: Ureteral injury from sutures during total hysterectomy is a relatively uncommon but potentially severe complication that can lead to serious sequelae such as ureterovaginal fistula or renal insufficiency. The management of such i…

BACKGROUND: Endometriosis affects approximately 10% of women of reproductive age and is associated with increased risks of infertility and miscarriage. Although the spontaneous miscarriage rate in women with endometriosis is higher than in …

OBJECTIVE: The malposition of the levonorgestrel-releasing intrauterine system (LNG-IUS) can have a considerable impact on the treatment outcomes for patients with adenomyosis. This study was designed to explore the relationship between the…

Vaginal natural orifice transluminal endoscopic surgery (vNOTES) offers several distinct advantages, including an optimal cosmetic result, early resumption of flatus and a shorter hospital stay. This minimally invasive approach has been inc…

Intrauterine adhesion (IUA) was characterized by endometrial fibrosis, leading primarily to hypomenorrhea, infertility and recurrent miscarriage. Epithelial-mesenchymal transition (EMT) is now recognized as a key factor in the development o…

The aim of the case control study was to compare surgical outcomes of transvaginal natural orifice transluminal endoscopic surgery (vNOTES) hysterectomy with the da Vinci surgical system (dVSS) and conventional vNOTES. A case control study …

BACKGROUND: While endometriosis is commonly perceived as a benign gynecological condition, its aggressive biological behavior underscores the critical importance of effective postoperative management. Our research is driven by the ultimate …

Indocyanine green (ICG), as the sole near-infrared dye FDA-approved, is limited in biomedical applications because of its poor photostability, lack of targeting, and rapid removal in vivo. Herein, we presented a nanoformulation of poly-l-ly…

In recent years, perfluoroalkyl substances (PFASs), a family of fluorinated organic com pounds, have garnered much attention due to their reproductive and developmental toxicity in humans. Polycystic ovary syndrome (PCOS) is a prevalent end…

Abstract Many studies have shown that endometriosis can lead to infertility in women of reproductive age, but the mechanism is unknown. Our study aims to explore the pathogenesis of stage IV endometriosis with infertility and the role of c…