Stephanie L. Skala

Mitigating DNA damage in the fallopian tube epithelium (FTE) is essential for preventing tubo-ovarian high-grade serous carcinoma (HGSC). In this study, we demonstrated that the stimulator of interferon genes (STING) is abundantly expressed…

Quantification of IHC staining for STING conducted on a tumor microarray including cores from healthy FT, FT from patients with gynecological inflammation resulting from endometriosis or chronic salpingitis, and Stage I/Stage II HGSC

= 53). The model achieved high sensitivity and specificity on the balanced validation cohort, with an area under the receiver operating characteristic curve (AUROC) of 0.96 (95% CI: 0.90-1.00), and demonstrated similarly strong performance …

Recent studies have provided molecular confirmation that a subset of yolk sac tumors is somatically derived. Somatically derived yolk sac tumors are typically diagnosed in older women and are often seen adjacent to epithelial proliferations…

This report describes 3 cases of ovarian tumors with unusual glandular proliferations co-expressing estrogen receptor and CDX-2 by immunohistochemistry set in cystadenofibromatous background. Targeted next-generation sequencing was performe…

Ovarian germ cell tumors, including yolk sac tumors, are most commonly diagnosed in children and young women. Most so-called yolk sac tumors reported in women >35 years old have been associated with an epithelial proliferation (endometriosi…