Blakely B

No ORCID on file · 1 paper in corpus · active 2023
2023
Overview of the therapeutic strategies for ER positive breast cancer.
Biochemical pharmacology ·doi:10.1016/j.bcp.2023.115552

Estrogen Receptor is the driving transcription factor in about 75% of all breast cancers, which is the target of endocrine therapies, but drug resistance is a common clinical problem. ESR1 point mutations at the ligand binding domain are fr…