McLachlan JA

No ORCID on file · 8 papers in corpus · active 1984-2008

Study types

  • review 2
  • other 1

Condition tags

  • endometriosis 3
review 2008
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.08.067

OBJECTIVE: To evaluate the possible role of endocrine-disrupting compounds (EDCs) on female reproductive disorders emphasizing developmental plasticity and the complexity of endocrine-dependent ontogeny of reproductive organs. Declining con…

review 2006
Best practice & research. Clinical endocrinology & metabolism ·doi:10.1016/j.beem.2005.09.009

There is growing evidence of the impact of estrogenic contaminants in the environment. Studies have shown that male fish in detergent-contaminated water express female characteristics, turtles are sex-reversed by polychlorinated biphenyls (…

2002
Environmental health perspectives ·doi:10.1289/ehp.021101239

Endocrine-disrupting organochlorines, such as the pesticide dichlorodiphenyltrichloroethane (DDT), bind to and activate estrogen receptors (ERs), thereby eliciting estrogen-like effects. Although ERs function predominantly through activatio…

1998
Environmental health perspectives ·doi:10.1289/ehp.98106787

Patterns of illness in American children have changed dramatically in this century. The ancient infectious diseases have largely been controlled. The major diseases confronting children now are chronic and disabling conditions termed the "n…

1995
Environmental health perspectives ·doi:10.1289/ehp.95103s73
other 1990
Cancer research

In order to study the effects of perinatal exposure to estrogens on the developing reproductive tract, outbred female mice were treated neonatally (days 1 to 5) with varying doses of diethylstilbestrol (DES) and sacrificed from 1 to 18 mont…

1986
The American Journal of Pathology

The association of prenatal exposure to diethylstilbestrol (DES) and abnormalities in structures of müllerian (paramesonephric) origin has been well documented. In a murine model, exposure to DES in utero results in persistent mesonephric r…

1984
The American Journal of Pathology