Zhang Y

We wished to ascertain if there is an association between neutrophil extracellular traps and endometriosis (EMS). We collected the lesional tissues and normal endometrium of 30 patients suffering from endometriosis. Samples were also taken …

Polycystic ovary syndrome is the primary cause of female infertility. Growing evidence suggests that dysregulation of amino acid metabolism plays a significant role in the onset and progression. However, the underlying mechanism remains unc…

BACKGROUND: Adenomyosis (AM) is a common benign gynecological disease, defined by the presence of endometrial glands and stroma deep within the myometrium, which is associated with hypertrophy and hyperplasia of the adjacent myometrium. It …

PurposeTo investigate the dynamic changes of serum Anti-Müllerian Hormone (AMH) and Inhibin B (INHB) during controlled ovarian hyperstimulation (COH) in patients with polycystic ovarian syndrome (PCOS) and analyze their correlation with COH…

BackgroundThe burden of comorbidities in those with uterine fibroids compared to those without fibroids is understudied. We performed a phenome-wide association study to systematically assess the association between fibroids and other condi…

BACKGROUND: The cervicovaginal microbiome-spanning from the vagina to endometrium-remains undercharacterized in endometriosis-associated infertility. Objective: To determine whether combined vaginal and cervical microbial profiles predict f…

PurposeThis study aims to create and validate a clinical prediction model to determine the optimal gonadotropin (Gn) starting dose in controlled ovarian stimulation (COS) protocols for normal ovarian response (NOR) patients undergoing their…

PurposeThe International Federation of Gynecology and Obstetric (FIGO) stage is critical to guiding the treatments of ovarian cancer (OC). We tried to develop a model to predict the FIGO stage of OC through machine learning algorithms with …

Repeated implantation failure (RIF) presents a significant challenge to in vitro fertilization (IVF), and abnormalities in the endometrium often play a crucial role in RIF. To enhance and deepen our understanding of tissue context in the en…

BackgroundA wealth of evidence indicates that dyslipidemia is associated with endothelial dysfunction, oxidative stress, and inflammation, each of which can impair reproductive function and lead to infertility. The Atherogenic Index of Plas…

BackgroundInflammation and high-density lipoprotein (HDL) metabolism are strongly linked to female infertility. The ratios of neutrophil-, lymphocyte-, platelet- and monocyte-to-HDL cholesterol (NHR, LHR, PHR, and MHR) are HDL-related infla…

ObjectivesTuberculosis (TB) is a common cause of infertility in humans, especially in regions with high TB prevalence. However, the impact of latent TB infection (LTBI) on pregnancy outcomes following assisted reproduction in patients with …

BackgroundInfertility in women of reproductive age is a major worldwide health problem. Oxidative stress, inflammatory responses, and dysregulation of lipid metabolism are among the factors that contribute to female infertility. The ratio o…

Background & objectiveTo assess the association of assisted reproductive technologies (ART) conception with postpartum hemorrhage (PPH) during the peripartum and postpartum periods.MethodsClinical records of 11,497 patients enrolled in Fuji…

BackgroundAlthough the dietary inflammatory index (DII) plays a vital role in human health, the association between the DII and women's menopausal status is still unclear. The aim of this study was to investigate the associations of the ene…

BackgroundPrevious studies have focused on the effects of ambient air pollutant levels on assisted reproduction. This research focused on the combined effects of lower concentrations of air pollutants and multiple environmental factors on m…

BackgroundTo a large extent, the ovarian reserve determines a woman's reproductive potential. The etiological and pathological mechanisms of diminished ovarian reserve (DOR) remain unclear, and no reliable treatment is currently available f…

Endometriosis is an estrogen dependent disease, which is related to infertility. Decidualization is a prerequisite for successful implantation of human embryos, and endometriosis affects the occurrence of decidualization. However, the mecha…

PurposeBecause hearing impairment as an invisible disability is not considered to have serious body image problems, the impact of body image on negative emotions of deaf or hard-of-hearing (DHH) college students has been relatively neglecte…

Endometriomas, commonly known as ovarian chocolate cysts, are a prevalent condition in women of reproductive age. They are cysts formed by the ectopic growth of endometrial tissue within the ovary, often leading to dysmenorrhea and infertil…

Hepatocellular carcinoma (HCC) mainly depends on liver fibrosis/cirrhosis, which is regulated by tumor cells and the tumor microenvironment (TME), and is a crucial factor in tumor progression. This study aimed to identify abnormally express…

Songwei Feng,1,* Yuru Wang,1,* Sicong Liu,2,* Yueming Zhang,1 Leilei He1 1Department of Obstetrics and Gynaecology, The Fourth Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China; 2Department of Obstetrics and Gyna…

INTRODUCTION: Endometriosis is a chronic gynecological disorder that significantly impacts women of reproductive age. Recent evidence suggests a bidirectional link between endometriosis and brain functional networks, though the causal mecha…

Abstract Endometriosis, affecting approximately 10% of reproductive-aged women worldwide, is a typical chronic inflammatory disease. Inflammation-related genes (IRGs) play a crucial role in the occurrence and progression of various disease…

Severe acute pancreatitis (SAP), a life-threatening inflammatory disease of the pancreas, has a high mortality rate (∼40 %). Current therapeutic approaches, including antibiotics, trypsin inhibitors, fasting, rehydration, and even continuou…