Li Yu

This study aimed to evaluate the efficacy of three distinct controlled ovarian stimulation (COS) protocols—long GnRH-agonist (GnRH-a) protocol, GnRH-antagonist (GnRH-ant) protocol, and mild-ovarian stimulation protocol—in endometriosis pati…

BACKGROUND: Polycystic ovary syndrome (PCOS) is widely acknowledged as the prevailing reproductive endocrine disorder accompanied by numerous metabolic dysfunctions. However, there has been a lack of systematic examination regarding the ami…

Large-scale deep endometrial injury has a serious impact on the reproductive health of women, necessitating the development of novel therapeutic approaches. Treatment strategies using single factor may not perfectly match the intricate and …

Abstract Study question Could human endometrial complex organoid be used to repair endometrial Injury and promote tissue regeneration? Summary answer The complex endometrial organoid we constructed can not only respond to hormonal stimulati…

BACKGROUND: Chronic salpingitis is one of the most common causes of female infertility. Luteal support is a critical step for embryo transfer. Here, we evaluated the effects of two luteal support regimens, intramuscular progesterone (IMP) a…

BACKGROUND: In previous retrospective studies, low serum progesterone level on the embryo transfer day is associated with lower clinical pregnancy and ongoing pregnancy rates. Whether adding progesterone in low serum progesterone patients c…

PURPOSE: Human follicular fluid (FF) is a complex biological fluid that contributes to the micro-environment of oocyte development. The aim of this study was to evaluate the role of steroid and gonadotropic hormones levels and mitochondrial…

In addition to liquid-based cytology (LBC) and HR HPV testing, p16/ki-67 dual-staining is another method for cervical cancer screening. The combination of any two methods can improve the accuracy of screening, but some cervical lesions are …

SUMMARY The human uterus is a highly dynamic tissue that undergoes repeated damage repair and regeneration during the menstrual cycle, which make it ideal model to study tissue regeneration and pathological process. Stem/progenitors were sp…

Spontaneous hemothorax due to anticoagulant use is extremely rare in clinical practice. Dabigatran is a novel anticoagulant to prevent stroke or thromboembolic episodes in patients with nonvalvular atrial fibrillation. We report on an 83-ye…

Endometrial adenocarcinoma is the most common tumour of the female genital tract in developed countries, and oestrogen receptor (ER) signalling plays a pivotal role in its pathogenesis. When we used bioinformatics tools to search for the ge…

OBJECTIVE: To evaluate the efficacy of laparoscopic conservative surgery plus gonadotropin-releasing hormone agonist (GnRH-a) in the treatment of endometriosis through meta-analysis. METHODS: Six randomized controlled clinical trials compa…

Chronic infection and inflammation are among the most important factors contributing to cancer development and growth. Toll-like receptors (TLRs) are important families of pattern recognition receptors, which recognize conserved components …

Objective:To study the efficacy of medroxyprogesterone in endometriosis after conservative surgery.Methods:From 1997 to 2000,102 women with endometriosis received conservative surgery in our hospital.They were divided into two groups.Group …

OBJECTIVE: To study the effect of TCTS on endometriosis rats. METHOD: On the model of surgical induced rat endometriosis, weight and pathological changes of endometrial transplant and serum hormones were observed. RESULT: Weight of endome…

Objective To investigate distribution pattern of the causes of female infertility. Methods The clinical data of 3 335 infertile women undergoing laparoscopic examination from January 1984 to March 1998 were retrospectively analyzed. Results…