Tingting Wang

PURPOSE: To investigate whether controlled ovarian stimulation (COS), as part of assisted reproductive technology (ART), accelerates the progression of BI-RADS categories. METHODS: This was a single-center, retrospective, propensity score …

PURPOSE: This study aims to compare the live birth rate (LBR) and reproductive outcomes between gonadotropin-releasing hormone antagonist (GnRH-ant) and progestin-primed ovarian stimulation (PPOS) protocols in infertile women of advanced re…

Primary vaginal cancer is a rare malignant tumor; its pathogenesis remains unclear and only a limited number of cases have been documented in the literature. The present report outlines a rare case of primary vaginal endometrioid adenocarci…

OBJECTIVES: Early menarche affects the mental and physical health of girls, but the evidence of the association between birth weight/rapid weight gain and early menarche is inconsistent. We conduct this systematic review and meta-analysis t…

PURPOSE: This study was designed to evaluate the effects of dual trigger (GnRH agonist and hCG) compared with hCG trigger alone on oocyte quality, embryo development, and pregnancy outcomes in elderly women (aged≥35 years) who underwent IVF…

Sterile and infection-associated inflammatory diseases are becoming increasingly prevalent worldwide. Conventional drug therapies often entail significant drawbacks, such as the risk of drug overdose, the development of drug resistance in p…

PURPOSE: Observational studies and clinical validation have suggested a link between thyroid dysfunction and an elevated ovarian cancer (OC) risk. However, whether this association indicates a cause-and-effect relationship remains uncertain…

The development of ovarian cancer is closely related to various factors, such as environmental, genetic and microbiological factors. In previous research, bacteria were identified in human tumors by 16S rRNA sequencing. However, the microbi…

Telomere attrition plays a critical role in the reproductive aging process in humans. Telomere length (TL) is typically regulated by telomerase, the main component of which is telomerase reverse transcriptase (TERT). The aim of the present …

Melatonin is important for oocyte maturation, fertilization, early embryonic development, and embryo implantation, but less knowledge is available regarding its role in decidualization. The present study found that melatonin did not alter t…

Relugolix, a gonadotropin-releasing hormone (GnRH) receptor antagonist, has been well studied in the treatment of endometriosis symptomatic. It is mainly metabolized by the CYP3A subfamily of P450 enzymes, while minorly metabolized by CYP2C…

OBJECTIVE: This study aimed to explore the effect of COX-2 selective inhibitor (celecoxib) on adenomyosis and its mechanism. METHODS: By establishing a mouse model of adenomyosis and using celecoxib to treat adenomyosis, newly born female …

ETHNOPHARMACOLOGICAL RELEVANCE: Bu Shen Huo Xue Tang (BSHXT) is a traditional Chinese medicine formula that is clinically used in the treatment of premature ovarian insufficiency (POI). However, its therapeutic mechanism remains unclear. A…

We performed a meta-analysis to assess the diagnostic accuracy of circulating miRNA for patients with ovarian cancer. We systematically searched several online databases, including PubMed, Web of Science, Chinese National Knowledge Infrastr…

OBJECTIVE: To assess the added value of diffusion-weighted magnetic resonance imaging (DWI) with apparent diffusion coefficient (ADC) values compared to MRI, for characterizing the tubo-ovarian abscesses (TOA) mimicking ovarian malignancy. …

Epithelial-mesenchymal transition (EMT) plays a specific role in the migration of tumor cells. Both estrogen and midkine (MK) have been thought to be important factors in promoting the progression of non-small-cell lung cancer (NSCLC) and c…

OBJECTIVE: Aquaporins (AQPs) may be involved in the occurrence of abnormal uterine bleeding as the mediators between ovarian steroids and cyclic endometrial changes. The aim of the present study was to investigate the characteristics of end…