Donatella Santini

Ovarian carcinomas represent a heterogeneous group of neoplasms consisting of separate entities with distinct risk factors, precursor lesions, pathogenesis, patterns of spread, molecular profiles, clinical course, response to chemotherapy, …

Since 2016, our hospital has applied tumor testing with immunohistochemistry (IHC) in endometrial cancer in order to detect mutations of mismatch repair genes (MMR). All cases with MMR deficiency proteins expression are sent for genetic tes…

Adenosarcomas are the rarest form of uterine sarcomas, and clinical experience with their management is still limited. Here, we reported 7 patients with uterine adenosarcoma referred to our institution, focusing on main pathologic features,…

BackgroundExtra-abdominal metastases in low grade endometrial carcinoma are rare events. Inguinal lymphatic spread occurs usually in advanced disease and is associated with abdominal lymph nodes involvement. To our knowledge, isolated ingui…

Post-caesarean endometritis is the most common cause of fever during the postpartum period. Severe intractable endometritis requiring hysterectomy is a rare but potentially life-threatening complication. The aim of our study was to describe…

The epidermal growth factor (EGF) and its receptor (EGFR) are involved in the control of the human endometrial growth [1]. The EGFR endometrial expression is up-regulated by estrogens [2]. The endometrial EGFR increases during the follicula…