Linrui Cai

No ORCID on file · 2 papers in corpus · active 2012-2023

Study types

  • article 1
  • rct 1

Condition tags

  • endometriosis 2
rct 2023
Safety, Pharmacokinetics, and Pharmacodynamics of SHR7280, a Non-peptide GnRH Antagonist in Premenopausal Women with Endometriosis: A Randomized, Double-Blind, Placebo-Controlled Phase 1 Study
Clinical pharmacokinetics ·doi:10.1007/s40262-023-01315-6

BACKGROUND: Oral gonadotropin-releasing hormone (GnRH) antagonists are promising agents in the treatment of endometriosis-related pain. Here we assessed the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of SHR7280, an oral non-pe…

article 2012
[The expression of Caspase-3 in granulosa cells of endometriosis treated with mifepristone].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

OBJECTIVE: To investigate the effect of mifepristone on the expression of Caspase-3 in the granulosa cells. METHODS: Forty Sprague-Dawley (SD) female rats with (230 +/- 20) g weight were divided into four groups, low-dose group with 1.04 mg…