A.M.C. Francisco

• Endometriosis is fueled by local estradiol accumulation that might be due to deficient HSD17B2 activity. • The microRNAs miR-124-3p and miR-26b-5p target the HSD17B2 gene. • This study measured miR-124-3p and miR-26b-5p in endometriotic l…

The limitations of current imaging methods to detect small or superficial endometriotic lesions prompt the search for new molecular targets. TSPO is an 18 KDa protein located in the outer mitochondrial membrane, which can be traced by posit…

Abstract Study question Is TSPO expressed in endometriotic lesions and negative in adjacent tissues, being eligible as a molecular target for noninvasive detection of endometriosis? Summary answer TSPO is detected in endometriotic lesions a…

Endometriosis implants are comprised of glandular and stromal elements, macrophages, nerves, and blood vessels and are commonly accompanied by pelvic pain. We propose that activated macrophages are recruited to and infiltrate nascent lesion…

ObjectiveTo evaluate neurotrophin (NT) expression in the endometrium of women with and without endometriosis.DesignProspective, cross-sectional, translational study.SettingAcademic hospital.Patient(s)Thirty-three reproductive-age women unde…