Newton-Bishop JA — Endo Lab

2014

The effect on melanoma risk of genes previously associated with telomere length.

Journal of the National Cancer Institute ·doi:10.1093/jnci/dju267

Telomere length has been associated with risk of many cancers, but results are inconsistent. Seven single nucleotide polymorphisms (SNPs) previously associated with mean leukocyte telomere length were either genotyped or well-imputed in 111…

2013

Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk.

Carcinogenesis ·doi:10.1093/carcin/bgs407

Genome-wide association studies (GWASs) have mainly focused on top significant single nucleotide polymorphisms (SNPs), most of which did not have clear biological functions but were just surrogates for unknown causal variants. Studying SNPs…

2011

Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3.

Nature genetics ·doi:10.1038/ng.958

We performed a genome-wide association study of melanoma in a discovery cohort of 2,168 Australian individuals with melanoma and 4,387 control individuals. In this discovery phase, we confirm several previously characterized melanoma-associ…