Satoshi Sasaki

ORCID: 0000-0002-6419-4495 · 3 papers in corpus · active 2008-2010

Study types

  • other 2
  • article 1

Condition tags

  • endometriosis 2
other 2010
2-acylamino-4,6-diphenylpyridine derivatives as novel GPR54 antagonists with good brain exposure and in vivo efficacy for plasma LH level in male rats
Bioorganic & medicinal chemistry ·doi:10.1016/j.bmc.2010.05.061

GPR54 is a G protein-coupled receptor (GPCR) which was formerly an orphan receptor. Recent functional study of GPR54 revealed that the receptor plays an essential role to modulate sex-hormones including GnRH. Thus, antagonists of GPR54 are …

other 2010
Synthesis and structure-activity relationships of 2-acylamino-4,6-diphenylpyridine derivatives as novel antagonists of GPR54
Bioorganic & medicinal chemistry ·doi:10.1016/j.bmc.2010.04.036

GPR54 is a G protein-coupled receptor (GPCR) which was formerly an orphan receptor. Recent functional study of GPR54 revealed that the receptor has an essential role to modulate sex-hormones including GnRH. Though antagonists of GPR54 are e…

article 2008
FokI Variant of Vitamin D Receptor Gene and Factors Related to Atherosclerosis Associated With Ossification of the Posterior Longitudinal Ligament of the Spine
·doi:10.1097/brs.0b013e31817e9de2

STUDY DESIGN: A sex- and age-matched case-control study with genotyping of the FokI variant of the vitamin D receptor gene (VDR) was carried out. OBJECTIVES: To facilitate the early prediction, prevention, and treatment of ossification of t…