Fang Chen

Introduction Adenomyosis is an enigmatic disease with estrogen dependence, and the exact pathogenic mechanisms remain confusing. Limited evidence points out the presence of gut flora changes in adenomyosis. However, evidence on how adenomyo…

Endometriosis (EMs) is a prevalent chronic gynecological condition that depends on estrogen, marked by the presence of active endometrial tissue (glands and stroma) outside the uterus. Although pathologically benign, it exhibits biological …

RESEARCH QUESTION: Does LncRNA BANCR promote the malignant transformation of endometriosis by activating the miR-612/CPNE3 pathway? DESIGN: The expression patterns of BANCR, miR-612 and CPNE3 in normal endometrium, eutopic endometrium from…

Fatty acids play important roles in maintaining ovarian steroidogenesis and endometrial receptivity. Porcine primary ovarian granulosa cells (PGCs) and endometrial epithelial cells (PEECs) were treated with or without medium- and short-chai…

OBJECTIVE: This study aimed to verify the role of basic fibroblast growth factor (bFGF)-bone mesenchymal stem cells (BMSCs) loaded on collagen scaffolds for the repair of injured endometrium. METHODS: days. The endometrium thickness, number…

BACKGROUND: To examine differences in the maternal characteristics and pregnancy outcomes of Chinese women with various causes of infertility who underwent in vitro fertilization (IVF) with embryonic cryopreservation treatment. METHODS: Ca…

PURPOSE: To investigate the potential role of Bone morphogenetic protein 1 (BMP1) in endometriosis lesions. METHODS: Endometriosis model in mice was established. The expression of BMP1-3 expression in mice of endometriosis lesions was eval…

BACKGROUND: To investigate the effect of applying doctor-nurse-patient integration management mode to patients with endometriosis (EMT). METHODS: A total of 160 patients with EMT from the Department of Neurology of The Fifth Affiliated Hosp…

Objective: To evaluate the effects of estradiol on endometrial regeneration and stromal fibrosis after endometrial curettage. Study Design: This is an experimental, prospective study. Combining ovariectomized rabbits and different doses of …

OBJECTIVE: To investigate the effect and mechanism of the formation of intrauterine adhesion (IUA) at different dose of estrogen. METHODS: Thirty-three New Zealand female rabbits were randomly divided into low estrogen group, normal physiol…