Segers I — Endo Lab

2022

Effect of A23187 ionophore treatment on human blastocyst development-a sibling oocyte study.

Journal of assisted reproduction and genetics ·doi:10.1007/s10815-022-02467-3

PurposeTo investigate whether treatment with commercially available ready-to-use A23187 ionophore (GM508-CultActive) improves embryo development outcome in patients with a history of embryo developmental problems.MethodsThis is a uni-center…

2022

First live birth after fertility preservation using vitrification of oocytes in a woman with mosaic Turner syndrome.

Journal of assisted reproduction and genetics ·doi:10.1007/s10815-022-02420-4

PurposeTo report the case of a young woman diagnosed with Turner syndrome (TS) who achieved a live birth using her own oocytes that had been vitrified for fertility preservation.MethodsA 25-year-old woman with mosaic (45,X/46,XX) TS was ref…

2019

Cumulus-corona gene expression analysis combined with morphological embryo scoring in single embryo transfer cycles increases live birth after fresh transfer and decreases time to pregnancy.

Journal of assisted reproduction and genetics ·doi:10.1007/s10815-018-01398-2

PurposeClinical pregnancy rate after IVF with eSET stagnates between 30 and 40%. In order to increase pregnancy and live birth rates, multiple embryo transfer is still common practice. Providing additional non-invasive tools to choose the c…

2013

Pregnancy prediction in single embryo transfer cycles after ICSI using QPCR: validation in oocytes from the same cohort.

PloS one ·doi:10.1371/journal.pone.0054226

Cumulus cell (CC) gene expression is being explored as an additional method to morphological scoring to choose the embryo with the highest chance to pregnancy. In 47 ICSI patients with single embryo transfer (SET), from which individual CC …