Rao B

ORCID: 0000-0002-2798-2468 · 4 papers in corpus · active 2010-2019
2019
Histogram analysis of en face scattering coefficient map predicts malignancy in human ovarian tissue.
Journal of biophotonics ·doi:10.1002/jbio.201900115

Ovarian cancer is a heterogeneous disease at the molecular and histologic level. Optical coherence tomography (OCT) is able to map ovarian tissue optical properties and heterogeneity, which has been proposed as a feature to aid in diagnosis…

2013
A recombinant adenovirus vector encoding the light chain of human coagulation factor VII and IgG1 Fc fragment to targeting tissue factor for colorectal cancer immunotherapy in the mouse model.
Journal of cancer research and clinical oncology ·doi:10.1007/s00432-013-1417-1

PurposeOver expression of tissue factor (TF) occurs in more than 50 % of colorectal cancer (CRC). Therefore, TF represents an attractive target antigen for immunotherapy in CRC.MethodsHere, we assessed the safety and efficacy of a recombina…

2011
Selective and effective killing of angiogenic vascular endothelial cells and cancer cells by targeting tissue factor using a factor VII-targeted photodynamic therapy for breast cancer.
Breast cancer research and treatment ·doi:10.1007/s10549-010-0957-1

The cell surface receptor tissue factor (TF) is regarded as a common but specific target on angiogenic tumor vascular endothelial cells (VECs) and tumor cells in many types of cancer including breast cancer. The purpose of this study is to …

2010
Targeting tissue factor on tumour cells and angiogenic vascular endothelial cells by factor VII-targeted verteporfin photodynamic therapy for breast cancer in vitro and in vivo in mice.
BMC cancer ·doi:10.1186/1471-2407-10-235

BackgroundThe objective of this study was to develop a ligand-targeted photodynamic therapy (tPDT) by conjugating factor VII (fVII) protein with photosensitiser verteporfin in order to overcome the poor selectivity and enhance the effect of…