Peter Lembessis

ORCID: 0000-0001-8972-3499 · 4 papers in corpus
article 2004
Glucocorticoid receptor function suppresses insulin-like growth factor 1 activity in human KLE endometrial-like cells.
In vivo (Athens, Greece)

We analysed the glucocorticoid receptor (GR) regulation on the expression of insulin-like growth factor 1 (IGF-1), type I IGF receptor (IGF-1.R), IGF-binding protein 3 (IGFBP-3), urokinase-type plasminogen activator (uPA) and uPA receptor (…

article 2003
Mutation analysis of BrCA1, BrCA2, and p53 versus soluble HLA class I and class II in a case of familial endometriosis
Fertility and sterility ·doi:10.1016/s0015-0282(02)04665-4

ObjectiveTo investigate possible correlation(s) between mutations of BrCA1, BrCA2, and p53 genes versus soluble HLA expression in familial endometriosis.DesignMutation analysis.SettingUniversity teaching departments and hospital.Patient(s)A…

article 2003
Urokinase‐Type Plasminogen Activator and Insulin‐Like Growth Factor‐Binding Protein 3 mRNA Expression in Endometriotic Lesions and Eutopic Endometrium
Annals of the New York Academy of Sciences ·doi:10.1196/annals.1290.025

The peritoneal fluid of women with endometriosis contains an increased insulin-like growth factor 1 (IGF-1) bioavailability, which is produced by limited hydrolysis of urokinase-type plasminogen activator (uPA) on IGF-binding protein 3 (IGF…

article 2001
Increased Insulin-like Growth Factor 1 Activity Can Rescue KLE Endometrial-like Cells from Apoptosis
Molecular medicine (Cambridge, Mass.) ·doi:10.1007/bf03401835

BACKGROUND: The peritoneal fluid (PF) of women with endometriosis contains protease(s) activity able to hydrolyze insulin-like growth factor-binding protein 3 (IGFBP-3), increasing the bioavailability of insulin-like growth factor-1 (IGF-1)…