Dan Longrois

No ORCID on file · 2 papers in corpus

review 2020

International Union of Basic and Clinical Pharmacology. CIX. Differences and Similarities between Human and Rodent Prostaglandin E2 Receptors (EP1-4) and Prostacyclin Receptor (IP): Specific Roles in Pathophysiologic Conditions

Pharmacological reviews ·doi:10.1124/pr.120.019331

Prostaglandins are derived from arachidonic acid metabolism through cyclooxygenase activities. Among prostaglandins (PGs), prostacyclin (PGI2) and PGE2 are strongly involved in the regulation of homeostasis and main physiologic functions. I…

nonrandomized-trial 2014

Decreased PGE₂ content reduces MMP-1 activity and consequently increases collagen density in human varicose vein

PloS one ·doi:10.1371/journal.pone.0088021

UNLABELLED: Varicose veins are elongated and dilated saphenous veins. Despite the high prevalence of this disease, its pathogenesis remains unclear. AIMS: In this study, we investigated the control of matrix metalloproteinases (MMPs) expre…