Wojciech Fendler
ORCID: 0000-0002-5083-9168
· 12 papers in corpus
other
2026
Hereditary breast and ovarian cancer syndrome (HBOC) is principally caused by germline mutations in BRCA1 and BRCA2. However, most women with HBOC are undiagnosed, and some patients meeting clinical criteria for HBOC will have no identifiab…
meta-analysis
2025
Abstract Background Lack of knowledge on the processes driving endometriosis hinders early detection and therapy development. Our purpose was to identify key molecular events involved in lesion formation across diverse populations and to de…
meta-analysis
2025
BACKGROUND: Molecular events that drive endometriosis (EM) and cause accompanying immune deregulation remain elusive. Our purpose was to identify key pathways involved in lesion formation across diverse populations and to detect transcripto…
2025
The dataset containing the results of network meta-analysis comparing gene expression in three tissue types: EL - endometriosis lesion, EEM -eutopic endometrium from women with endometriosis, EH - eutopic endometrium from women without endo…
2025
The dataset containing the results of network meta-analysis comparing gene expression in three tissue types: EL - endometriosis lesion, EEM -eutopic endometrium from women with endometriosis, EH - eutopic endometrium from women without endo…
other
2025
BACKGROUND: Serum miRNAs are potential biomarkers for ovarian cancer; however, many factors may influence miRNA expression. To understand potential confounders in miRNA analysis, we examined how sociodemographic factors and comorbidities, i…
review
2025
Chronic pain is a defining feature of endometriosis and contributes significantly to the diminished quality of life observed in affected individuals. Despite advances in understanding disease pathology, current therapeutic strategies largel…
2025
other
2024
INTRODUCTION: Prior studies have investigated the diagnostic potential of microRNA (miRNA) expression profiles for endometriosis. However, the vast majority of previous studies have only included adult women. Therefore, we sought to investi…
other
2024
OBJECTIVE: To determine whether a multimodal assay combining serum microRNA with protein biomarkers and metadata improves triage assessment of an adnexal mass. METHODS: Serum samples from 468 training subjects (191 cancer cases and 277 ben…
other
2020
BACKGROUND: The consensus on how to choose a reference gene for serum or plasma miRNA expression qPCR studies has not been reached and none of the potential candidates have yet been convincingly validated. We proposed a new in silico approa…
diagnostic-accuracy
2017
Recent studies posit a role for non-coding RNAs in epithelial ovarian cancer (EOC). Combining small RNA sequencing from 179 human serum samples with a neural network analysis produced a miRNA algorithm for diagnosis of EOC (AUC 0.90; 95% CI…