Murphy PR
No ORCID on file
· 2 papers in corpus
2014
Chromatin-remodeling factors mediate the balance of sense-antisense transcription at the FGF2 locus.
Antisense transcription is prevalent in mammalian genomes, yet the function of many antisense transcripts remains elusive. We have previously shown that the fibroblast growth factor 2 (FGF2) gene is regulated endogenously by an overlapping …
2012
Basic fibroblast growth factor (FGF2) is a potent wide-spectrum mitogen whose overexpression is associated with immortalization and unregulated cell proliferation in many tumors. The FGF2 gene locus is bi-directionally transcribed to produc…