Chiney MS

No ORCID on file · 1 paper in corpus

2022

Physiologically based pharmacokinetic modeling and simulations to inform dissolution specifications and clinical relevance of release rates on elagolix exposure.

Biopharmaceutics & drug disposition ·doi:10.1002/bdd.2315

The aim of this analysis was to use a physiologically based pharmacokinetic (PBPK) model to predict the impact of changes in dissolution rates on elagolix exposures and define clinically relevant acceptance criteria for dissolution. Varying…