M. M. Misro

No ORCID on file · 3 papers in corpus
lab-animal 2012
Complete sperm suppression induced by dienogest plus testosterone undecanoate is associated with down-regulation in the expression of upstream steroidogenic enzyme genes in rat testis
Contraception ·doi:10.1016/j.contraception.2011.11.020

BACKGROUND: We had shown that dienogest (DNG) + testosterone undecanoate (TU) induced complete sperm suppression in rats when administered together every 45 days. On the other hand, individual drugs given alone in a similar fashion failed t…

lab-animal 2011
Extended intervention time and evaluation of sperm suppression by dienogest plus testosterone undecanoate in male rat
Contraception ·doi:10.1016/j.contraception.2011.04.010

BACKGROUND: The potential of using dienogest [DNG, 40 mg/kg body weight (bw)] plus testosterone undecanoate (TU, 25 mg/kg bw) in rats for development of a once-a-month male hormonal contraceptive has been reported earlier in our laboratorie…

lab-animal 2009
Trials for development of once-a-month injectable, hormonal male contraceptive using dienogest plus testosterone undecanoate: dose standardization, efficacy and reversibility studies in rats
Contraception ·doi:10.1016/j.contraception.2009.01.003

BACKGROUND: The study was conducted to test the potential of using dienogest (DNG) plus testosterone undecanoate (TU) in rats for development of a once-a-month injectable male hormonal contraceptive. STUDY DESIGN: Dose selection studies we…