Dougherty MC

ORCID: 0000-0003-3247-0261 · 1 paper in corpus

lab-animal 2023

Reduction of sporadic and neurofibromatosis type 2-associated vestibular schwannoma growth in vitro and in vivo after treatment with the c-Jun N-terminal kinase inhibitor AS602801

Journal of neurosurgery ·doi:10.3171/2022.7.jns22934

OBJECTIVE: Vestibular schwannomas (VSs) are benign nerve sheath tumors that result from mutation in the tumor suppressor gene NF2, with functional loss of the protein merlin. The authors have previously shown that c-Jun N-terminal kinase (J…