Smith JA

ORCID: 0000-0001-8837-4928 · 1 paper in corpus

2022

Safety, Pharmacodynamics, and Pharmacokinetics of P2X3 Receptor Antagonist Eliapixant (BAY 1817080) in Healthy Subjects: Double-Blind Randomized Study.

Clinical pharmacokinetics ·doi:10.1007/s40262-022-01126-1

Background and objectiveThere is no licensed treatment for refractory chronic cough; off-label therapies have limited efficacy and can produce adverse effects. Excessive adenosine triphosphate signaling via P2X3 receptors is implicated in r…