Kevin Pagel

No ORCID on file · 1 paper in corpus · active 2025
2025
·doi:10.1101/2025.03.28.645909

HMGB1, a nuclear DNA-binding protein, can be secreted by activated immune cells or passively released from damaged cells. In such cases, HMGB1 functions as an alarmin that activates the immune system. Excessive inflammation may lead to path…