Ann K. Folkins — Endo Lab

lab-animal 2020

Omental macrophages secrete chemokine ligands that promote ovarian cancer colonization of the omentum via CCR1

Communications biology ·doi:10.1038/s42003-020-01246-z

The omentum is the most common site of ovarian cancer metastasis. Immune cell clusters called milky spots are found throughout the omentum. It is however unknown if these immune cells contribute to ovarian cancer metastasis. Here we report …

observational 2009

Epidemiologic correlates of ovarian cortical inclusion cysts (CICs) support a dual precursor pathway to pelvic epithelial cancer

Gynecologic Oncology ·doi:10.1016/j.ygyno.2009.06.032

OBJECTIVE: Many ovarian carcinomas are presumed to arise within ovarian cortical inclusion cysts (CICs). This study examined the frequency of ovarian CICs in relation to epidemiologic risk factors in women with BRCA1 and BRCA2 (BRCA+) mutat…

observational 2008

A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutations

Gynecologic Oncology ·doi:10.1016/j.ygyno.2008.01.012

BACKGROUND: Early serous carcinomas predominate in the fimbria of women with BRCA mutations (BRCA+). An entity in non-neoplastic mucosa sharing several properties of early serous carcinomas--the "p53 signature"--has been described in the di…

review 2008

Tubal and ovarian pathways to pelvic epithelial cancer: a pathological perspective

Histopathology ·doi:10.1111/j.1365-2559.2007.02938.x

Prolongation of ovarian epithelial cancer survival depends on early detection or improved responses to chemotherapy. Gains in either have been modest at best. Understanding the diverse pathogenesis of this disease is critical to early inter…