Zhou Y

This cross-sectional study investigated galectin-1, -3, and -9 in adenomyosis. Analysis of hysterectomy tissues from premenopausal women via western blot, qPCR, immunohistochemistry, and Masson's staining revealed significantly elevated gal…

Acyl-CoA synthetase long-chain family member 4 (ACSL4) is a key enzyme that catalyzes the conjugation of long-chain fatty acids with coenzyme A to form acyl-CoA, showing particularly high specificity for polyunsaturated fatty acids. In rece…

OBJECTIVE: Polycystic ovary syndrome (PCOS) is a multifactorial endocrine disorder characterized by reproductive and metabolic abnormalities. This study aimed to identify key immunometabolic regulators in endometrial tissue and construct a …

OBJECTIVE: This study aims to propose a novel, reproducible transvaginal ultrasound (TVUS) measurement-anterior-posterior wall thickness of the uterine isthmus ratio (APTUIR)-and to construct a nomogram model integrating this parameter with…

BACKGROUND: Adenomyosis has garnered increasing attention for its association with adverse pregnancy outcomes in recent years. However, findings across studies remain inconsistent. This meta-analysis of cohort studies evaluated the impact o…

Catalpol, an iridoid glycoside predominantly derived from the fresh or dried root tuber of Rehmannia glutinosa Libosch (a member of the Scrophulariaceae family), it is a representative compound with the highest content in Rehmannia glutinos…

PURPOSE: This study aimed to summarize the clinical characteristics, surgical management, and follow-up outcomes of patients with severe renal impairment caused by ureteral endometriosis. METHODS: We conducted a retrospective analysis of t…

This study utilized the Surveillance, Epidemiology, and End Results (SEER) database to identify clinicopathological prognostic factors and develop a prognostic nomogram for predicting 1-, 3-, and 5-year overall survival (OS) in patients wit…

The homeostasis balance of copper, as an essential trace element for life activities, is crucial for maintaining the normal function of cells. Cuproptosis, discovered in recent years, is a novel type of programmed cell death triggered by th…

BACKGROUND: Recurrent implantation failure (RIF) is a major challenge in in vitro fertilization (IVF). The window of implantation (WOI) is the endometrium’s receptive period for embryos, and endometrial receptivity analysis (ERA) is a poten…

INTRODUCTION: The objective of this study was to examine the impact of semaphorin 3F (SEMA3F) on the proliferation, migration and ferroptosis of endometrial stromal cells in patients with endometriosis (EMS). METHODS: This study collected …

BACKGROUND: Endometriosis (EMs) is one of the most common gynecologic diseases, and the roles of ferroptosis in EMs have not been fully clarified. The induction of ferroptosis has been demonstrated to inhibit the growth of ectopic lesions i…

BackgroundCesarean delivery often results in both abdominal wall scars and uterine scars. However, current rehabilitation strategies for cesarean-related scars lack standardization and a biomechanically informed framework that integrates su…

Metabolic dysfunction-associated steatotic liver disease (MASLD) is highly prevalent and associated with metabolic dysfunction, systemic inflammation, and increased cardiovascular risk. The C-reactive protein-Triglyceride-Glucose Index (CTI…

BackgroundVaricocele represents the most prevalent amendable factor contributing to male infertility. Despite this, considerable debate continues concerning the effectiveness of surgical intervention, especially in terms of enhancing pregna…

BACKGROUND: Chronic pain resulting from postoperative adhesions represents a significant clinical concern due to its substantial impact on patient quality of life; however, optimal therapeutic management remains contentious. This systematic…

The cryopreservation of ovarian tissue can induce oxidative damage. In this study, we investigated whether low-intensity pulsed ultrasound (LIPUS) can mitigate this oxidative damage and examined the underlying molecular mechanisms. Ovarian …

BackgroundSalpingitis is a leading cause of female infertility and ectopic pregnancy worldwide. Despite advances in reproductive medicine, its early diagnosis and effective prevention of long-term sequelae remain challenging due to its ofte…

Nociplastic pain (NPP) is a recently defined form of chronic pain, characterized by altered nociception in the absence of clear evidence of nociceptive or neuropathic pain. It is believed to be driven by maladaptive changes in nociceptive p…

Precise staging of endometriosis remains a clinical challenge, as current diagnosis depends almost entirely on laparoscopic visualization-an invasive procedure marked by considerable inter-observer disagreement and diagnostic delays. Existi…

Clinical application of mesenchymal stem cells for endometrial repair has been hampered by variability in cell quality, large-scale production, and uncertainty regarding the optimal delivery route. In this study, we investigated the therape…

Infertility affects ~1 in 6 people of reproductive age and remains difficult to treat because causes are heterogeneous and diagnostics are incomplete. Recent evidence reframes the female reproductive tract as a low-biomass but biologically …

BackgroundInfertility affects many couples worldwide, and the accurate assessment of endometrial receptivity (ER) is critical. However, conventional ultrasound has limited predictive value. Multiparameter quantitative ultrasound is a promis…

AimTo evaluate the predictive value of serum beta-human chorionic gonadotropin (β-hCG) measured at 11-14 days after frozen-thawed embryo transfer (FET) for clinical pregnancy, and to explore the potential associations of blastocyst transfer…

BackgroundAbnormalities in ureteral motility often precede morphological changes, and early subtle lesions are easily overlooked, thereby increasing the risk of renal impairment. However, existing imaging assessments tend to focus on qualit…