Li HL

No ORCID on file · 2 papers in corpus

lab-animal 2021

Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex

Acta pharmacologica Sinica ·doi:10.1038/s41401-020-00605-0

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by toxic aggregates of mutant huntingtin protein (mHTT) in the brain. Decreasing mHTT is a potential strategy for therapeutic purpose of HD. Valosin-contai…

observational 2020

Ovary and uterus related adverse events associated with statin use: an analysis of the FDA Adverse Event Reporting System

Scientific reports ·doi:10.1038/s41598-020-68906-2

Experimental studies have demonstrated statin-induced toxicity for ovary and uterus. However, the safety of statins on the functions of ovary and uterus in real-world clinical settings remains unknown. The aim of this study was to identify …