Le S

No ORCID on file · 1 paper in corpus

2013

A recombinant adenovirus vector encoding the light chain of human coagulation factor VII and IgG1 Fc fragment to targeting tissue factor for colorectal cancer immunotherapy in the mouse model.

Journal of cancer research and clinical oncology ·doi:10.1007/s00432-013-1417-1

PurposeOver expression of tissue factor (TF) occurs in more than 50 % of colorectal cancer (CRC). Therefore, TF represents an attractive target antigen for immunotherapy in CRC.MethodsHere, we assessed the safety and efficacy of a recombina…