Haofei Shen

ORCID: 0000-0003-0089-8861 · 2 papers in corpus

article 2024

Predicting the therapeutic role and potential mechanisms of Indole-3-acetic acid in diminished ovarian reserve based on network pharmacology and molecular docking

·doi:10.1186/s41065-024-00348-6

BACKGROUND: Indole-3-acetic acid (IAA), an indole analog produced by intestinal microorganisms metabolizing tryptophan, has anti-inflammatory and antioxidant properties and thus has potential applications in ovarian protection, although the…

article 2023

Determination of tryptophan and its indole metabolites in follicular fluid of women with diminished ovarian reserve

Scientific reports ·doi:10.1038/s41598-023-44335-9

Tryptophan (TRP) and its indole metabolites exhibit numerous biological effects, especially their antioxidant properties. This study used untargeted metabolomics in conjunction with targeted metabolomics to investigate the differential expr…