Pauli Saarenketo

No ORCID on file · 2 papers in corpus · active 2006-2009

Study types

  • other 2

Condition tags

  • endometriosis 2
other 2009
Estrone C15 derivatives--a new class of 17beta-hydroxysteroid dehydrogenase type 1 inhibitors
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2008.10.022

Lowering local estradiol concentration by inhibition of the estradiol-synthesizing enzyme 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) has been proposed as a promising new therapeutic option to treat estrogen-dependent diseases …

other 2006
New inhibitors of 17beta-hydroxysteroid dehydrogenase type 1
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2005.11.044

The estradiol-synthesizing enzyme 17beta-hydroxysteroid dehydrogenase type 1 (17betaHSD1) is mainly responsible for the conversion of estrone (E1) to the potent estrogen estradiol (E2). It is a key player to control tissue levels of E2 and …