Peter Carmeliet

ORCID: 0000-0001-7961-1821 · 2 papers in corpus · active 2018-2024

Study types

  • article 2
article 2024
Limiting Premenstrual Endometrial Hypoxia Inducible Factor 2 Alpha May Fine-Tune Endometrial Function at Menstruation
·doi:10.1210/clinem/dgae630

CONTEXT: Heavy menstrual bleeding (HMB) is common and debilitating, but the precise endometrial mechanisms causing increased menstrual blood loss (MBL) remain undefined. We have previously identified a role for hypoxia in endometrial repair…

article 2018
Hypoxia and hypoxia inducible factor-1α are required for normal endometrial repair during menstruation
·doi:10.1038/s41467-017-02375-6

Heavy menstrual bleeding (HMB) is common and debilitating, and often requires surgery due to hormonal side effects from medical therapies. Here we show that transient, physiological hypoxia occurs in the menstrual endometrium to stabilise h…