Peter Carmeliet

ORCID: 0000-0001-7961-1821 · 3 papers in corpus
article 2024
Limiting Premenstrual Endometrial Hypoxia Inducible Factor 2 Alpha May Fine-Tune Endometrial Function at Menstruation
The Journal of clinical endocrinology and metabolism ·doi:10.1210/clinem/dgae630

CONTEXT: Heavy menstrual bleeding (HMB) is common and debilitating, but the precise endometrial mechanisms causing increased menstrual blood loss (MBL) remain undefined. We have previously identified a role for hypoxia in endometrial repair…

2022
Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast.
Nature communications ·doi:10.1038/s41467-022-33052-y

Since a detailed inventory of endothelial cell (EC) heterogeneity in breast cancer (BC) is lacking, here we perform single cell RNA-sequencing of 26,515 cells (including 8433 ECs) from 9 BC patients and compare them to published EC taxonomi…

article 2018
Hypoxia and hypoxia inducible factor-1α are required for normal endometrial repair during menstruation
Nature communications ·doi:10.1038/s41467-017-02375-6

Heavy menstrual bleeding (HMB) is common and debilitating, and often requires surgery due to hormonal side effects from medical therapies. Here we show that transient, physiological hypoxia occurs in the menstrual endometrium to stabilise h…