Fan P

No ORCID on file · 13 papers in corpus
2025
Journal of orthopaedic surgery and research ·doi:10.1186/s13018-025-06451-2

BackgroundChat-Generative Pretrained Transformer (ChatGPT) has proven its value in medical information acquisition and perioperative education. This study aimed to evaluate correlated factors to explore the value of ChatGPT in patient commu…

2025
Frontiers in endocrinology ·doi:10.3389/fendo.2025.1644373

BackgroundOxidative stress and metabolic disorders significantly contribute to the development of polycystic ovarian syndrome (PCOS). Heme oxygenase-1 (HMOX1) plays a key role in the degradation of heme and the regulation of oxidative stres…

2024
Endocrine connections ·doi:10.1530/ec-23-0463

Oxidative stress and metabolic disorders are involved in the pathogenesis of polycystic ovary syndrome (PCOS). Heme oxygenase 2 (HMOX2) plays a critical role in preserving heme metabolism as well as in modulating glycolipid metabolism, oxid…

article 2024
International journal of molecular sciences ·doi:10.3390/ijms25158143

Endometriosis, often associated with chronic pelvic pain, can lead to anxiety and depression. This study investigates the role and mechanism of Glycine receptor alpha 3 (Glrα3) in the central sensitization of pain in endometriosis, aiming t…

2023
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-023-01139-w

BackgroundChildbearing in women with advanced maternal age (AMA) has increased the need for artificial reproductive technology (ART). ART and oxidative stress are associated with many pregnancy complications. Paraoxonase (PON) 1 is one of t…

2023
Biomedicine hub ·doi:10.1159/000535508

BackgroundMenopause in women marks the knot of reproductive life, and menopause is defined as the last menstrual period in a woman, but this is caused by the failure of the ovarian reserve. The average age of natural menopause in the genera…

review 2022
Expert reviews in molecular medicine ·doi:10.1017/erm.2022.26

Endometriosis is a chronic inflammatory disease with pelvic pain and uncharacteristic accompanying symptoms. Endometriosis-associated pain often persists despite treatment of the disease, thus it brings a deleterious impact on their persona…

2021
Cell death & disease ·doi:10.1038/s41419-021-03554-6

Ovarian cancer (OC) causes more deaths than any other gynecological cancer. Many cellular pathways have been elucidated to be associated with OC development and progression. Specifically, the insulin-like growth factor 1 receptor/insulin re…

2019
Frontiers in endocrinology ·doi:10.3389/fendo.2019.00771

Background: Oxidative stress plays an important role in the pathogenesis of polycystic ovary syndrome (PCOS). Glutathione peroxidase 1 (GPx1) and catalase (CAT) are the major intracellular antioxidant enzymes that can detoxify hydrogen pero…

2018
Lipids in health and disease ·doi:10.1186/s12944-018-0725-5

BackgroundElevated serum levels of apolipoprotein (apo) C1 may be an early protein marker of metabolic abnormality in women with polycystic ovary syndrome (PCOS). It is not clear, however, whether there are any relationships between the apo…

article 2018
Trials ·doi:10.1186/s13063-018-2684-6

BACKGROUND: Endometriosis is a chronic gynecological disease that is characterized by the presence of endometrial tissue outside the uterine cavity. The main symptoms include dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. …

2017
Lipids in health and disease ·doi:10.1186/s12944-017-0448-z

BackgroundThe G994T polymorphism in platelet-activating factor acetylhydrolase (PAF-AH) gene is associated with the risk of polycystic ovary syndrome (PCOS). The aim of this study was to investigate the relationship between R92H and A379V v…

article 2017
Evidence-based complementary and alternative medicine : eCAM ·doi:10.1155/2017/6489427

Endometriosis is a common gynecological condition in childbearing age women and its therapy in modern medicine achieves usually temporary cure. Ping-Chong-Jiang-Ni formula (PCJNF), a Chinese herbal medicine (CHM), was shown to be clinically…