Britta Weigelt

ORCID: 0000-0001-9927-1270 · 5 papers in corpus
preprint 2023
Data from PI3K Pathway Dependencies in Endometrioid Endometrial Cancer Cell Lines
·doi:10.1158/1078-0432.c.6522264

AbstractPurpose: Endometrioid endometrial cancers (EEC) frequently harbor coexisting mutations in phosphoinositide 3-kinase (PI3K) pathway genes, including PTEN, PIK3CA, PIK3R1, and KRAS. We sought to define the genetic determinants of PI3K…

preprint 2023
Data from PI3K Pathway Dependencies in Endometrioid Endometrial Cancer Cell Lines
·doi:10.1158/1078-0432.c.6522264.v1

AbstractPurpose: Endometrioid endometrial cancers (EEC) frequently harbor coexisting mutations in phosphoinositide 3-kinase (PI3K) pathway genes, including PTEN, PIK3CA, PIK3R1, and KRAS. We sought to define the genetic determinants of PI3K…

article 2022
EP111/#458 Sectioning and extensively examining the fimbriated end of fallopian tubes for endometrial cancer
·doi:10.1136/ijgc-2022-igcs.202
other 2022
Molecular Subclasses of Clear Cell Ovarian Carcinoma and Their Impact on Disease Behavior and Outcomes
Clinical cancer research : an official journal of the American Association for Cancer Research ·doi:10.1158/1078-0432.CCR-21-3817

PURPOSE: To identify molecular subclasses of clear cell ovarian carcinoma (CCOC) and assess their impact on clinical presentation and outcomes. EXPERIMENTAL DESIGN: We profiled 421 primary CCOCs that passed quality control using a targeted…

2022
Mullerian adenosarcoma: clinicopathologic and molecular characterization highlighting recurrent BAP1 loss and distinctive features of high-grade tumors.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc ·doi:10.1038/s41379-022-01160-1

Mullerian adenosarcoma is an uncommon mesenchymal tumor of the gynecologic tract. Most cases are low-grade, while high-grade adenosarcomas are rare and not well studied. Herein, we characterize the clinicopathologic and molecular features o…