Cheng JC

No ORCID on file · 2 papers in corpus

2026

piR-26681 suppresses ovarian cancer progression by enhancing METTL3/METTL14-mediated m6A modification of FBXO16 and impairing DNA repair via MORF4L1 degradation.

Cellular & molecular biology letters ·doi:10.1186/s11658-026-00969-x

BackgroundSurvival rates for ovarian cancer drop sharply at late-stages due to late diagnosis. Although PARP inhibitors are effective in homologous recombination-deficient (HRD) tumors, their efficacy in homologous recombination (HR)-profic…

2021

Role of sirtuins in bone biology: Potential implications for novel therapeutic strategies for osteoporosis.

Aging cell ·doi:10.1111/acel.13301

The decline in bone mass and bone strength and musculoskeletal problems associated with aging constitute a major challenge for affected individuals and the healthcare system globally. Sirtuins 1-7 (SIRT1-SIRT7) are a family of nicotinamide …