Sriram S

No ORCID on file · 2 papers in corpus

2025

REST missense mutations reveal disrupted Re1 motif binding and co-repressor interactions in uterine fibroids.

Frontiers in bioinformatics ·doi:10.3389/fbinf.2025.1703356

IntroductionThe Re1-Silencing Transcription Factor (REST) is a master regulator of gene silencing, orchestrating transcriptional repression by tethering chromatin-modifying co-repressors to the Re1 motif of target genes. While REST is recog…

2024

Midwife-Led Versus Obstetrician-Led Perinatal Care for Low-Risk Pregnancy: A Systematic Review and Meta-Analysis of 1.4 Million Pregnancies.

Journal of clinical medicine ·doi:10.3390/jcm13226629

Background: The optimum model of perinatal care for low-risk pregnancies has been a topic of debate. Obstetrician-led care tends to perform unnecessary interventions, whereas the quality of midwife-led care has been subject to debate. This …