Al-Hendy A

No ORCID on file · 52 papers in corpus

article 2008

Toward gene therapy of endometriosis: transductional and transcriptional targeting of adenoviral vectors to endometriosis cells

American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2008.01.059

ObjectiveThe purpose of this study was to screen a panel of targeted adenoviruses as vectors for endometriosis gene therapy.Study designEndometriotic cells were obtained from subjects with ovarian endometriomas. Liver tissues were taken fro…

other 2007

Toward gene therapy of endometriosis: adenovirus-mediated delivery of dominant negative estrogen receptor genes inhibits cell proliferation, reduces cytokine production, and induces apoptosis of endometriotic cells

Fertility and sterility ·doi:10.1016/j.fertnstert.2006.11.046

OBJECTIVE: To use dominant negative mutants of estrogen receptor genes delivered to endometriosis cells via an adenovirus vector (Ad-DN-ER) to abrogate estrogen action on these cells. DESIGN: Experimental in vitro study. SETTING: Universi…