Wenxiu CHENG

No ORCID on file · 4 papers in corpus · active 2025

Study types

  • article 3
  • review 1

Condition tags

  • adenomyosis 2
  • endometriosis 1
article 2025
Clinical efficacy and safety of Chinese patent medicines combined with hormonal therapy for endometriosis after laparoscopic surgery: A Bayesian network meta-analysis
Complementary therapies in clinical practice ·doi:10.1016/j.ctcp.2025.102020
review 2025
Mitochondrial homeostasis: A key regulator in endometrial physiology and pathology
·doi:10.1016/j.drudis.2025.104519

Endometrial cyclic remodeling and decidualization are critical physiological processes for female reproductive function and are profoundly influenced by mitochondrial homeostasis. Mitochondrial homeostasis is maintained through the mitochon…

article 2025
Study on the mechanism of <italic>Neiyi Kangfu Tablet</italic> (内异康复片) in ameliorating fibrosis of adenomyosis based on the IL-6/STAT3 pathway
·doi:10.70976/j.1008-0805.szgygy-2025-1003

目的 探讨内异康复片对小鼠子宫腺肌病纤维化的影响，并探讨其对IL-6/STAT3信号通路的调控作用。 方法 采用枸橼酸他莫昔芬滴喂的方法制备子宫腺肌病纤维化小鼠模型，70日龄小鼠采用低、中、高剂量的内异康复制剂及地诺孕素分别给药治疗，灌胃期间比较各组小鼠不同时间段的热痛阈值，灌胃治疗8周后取样，HE及Masson染色观察子宫组织病理学，Western Blot检测小鼠子宫组织中STAT3、p-STAT3的蛋白表达含量，ELISA测定血清中IL-6、TGF-β1、MCP-…

article 2025
Study on the mechanism of <italic>Neiyi Kangfu Tablet</italic>（内异康复片） in regulating macrophage polarization in adenomyosis mice
·doi:10.70976/j.1008-0805.szgygy-2025-2201

目的 探索内异康复片通过JAK2/STAT3通路调控子宫腺肌病小鼠巨噬细胞极化的作用机制。 方法 将造模成功的子宫腺肌病小鼠随机分为模型组、内异康复低/中/高剂量组、地诺孕素组。另设对照组。干预8周。采用热测痛仪评估疼痛敏感度；HE染色观察子宫病理形态；RT-qPCR和Western blot测定JAK2/STAT3通路相关因子mRNA的表达及磷酸化水平；免疫组化分析iNOS、Arg-1、IL-12A、IL-10的表达差异。 结果 模型组小鼠痛觉敏感度升高（P<0.…