Yap YHY

ORCID: 0000-0003-0739-8667 · 1 paper in corpus

2022

Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus.

BMC biology ·doi:10.1186/s12915-022-01410-3

BackgroundProgesterone receptor (PGR) is a master regulator of uterine function through antagonistic and synergistic interplays with oestrogen receptors. PGR action is primarily mediated by activation functions AF1 and AF2, but their physio…