Wang TL

No ORCID on file · 33 papers in corpus · active 2009-2026

Study types

  • article 5
  • other 4
  • case-report 1
  • editorial 1
  • review 1

Condition tags

  • endometriosis 12
  • adenomyosis 2
  • infertility 1
  • die_deep_infiltrating 1
2011
ARID1A, a factor that promotes formation of SWI/SNF-mediated chromatin remodeling, is a tumor suppressor in gynecologic cancers.
Cancer research ·doi:10.1158/0008-5472.can-11-1562

ARID1A (BAF250A) promotes the formation of SWI/SNF chromatin remodeling complexes containing BRG1 or BRM. It has emerged as a candidate tumor suppressor based on its frequent mutations in ovarian clear cell and endometrioid cancers and in u…

2011
Mutation and loss of expression of ARID1A in uterine low-grade endometrioid carcinoma.
The American journal of surgical pathology ·doi:10.1097/pas.0b013e318212782a

ARID1A is a recently identified tumor suppressor gene that is mutated in approximately 50% of ovarian clear cell and 30% of ovarian endometrioid carcinomas. The mutation is associated with loss of protein expression as assessed by immunohis…

2011
Rsf-1 (HBXAP) expression is associated with advanced stage and lymph node metastasis in ovarian clear cell carcinoma.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/pgp.0b013e3181e9a319

Ovarian clear cell carcinoma (CCC) is a unique type of ovarian cancer characterized by distinct clinicopathological and molecular features. CCC is considered to be a highly malignant disease because it is resistant to conventional chemother…

2011
Somatic mutations of PPP2R1A in ovarian and uterine carcinomas.
The American Journal of Pathology ·doi:10.1016/j.ajpath.2011.01.009

Exome sequencing of ovarian clear-cell carcinoma has identified somatic mutations in PPP2R1A, a subunit of protein phosphatase 2A. The present study was performed to determine the frequency of PPP2R1A mutations in exon 5, which harbors prev…

2011
Telomere length in different histologic types of ovarian carcinoma with emphasis on clear cell carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc ·doi:10.1038/modpathol.2011.67

Ovarian carcinoma is composed of a heterogeneous group of tumors with distinct clinico-pathological and molecular features. Alteration of telomerase activity has been reported in ovarian tumors but the pattern of telomere length in their sp…

2010
DNA copy numbers profiles in affinity-purified ovarian clear cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research ·doi:10.1158/1078-0432.ccr-09-2105

PurposeAdvanced ovarian clear cell carcinoma (CCC) is one of the most aggressive ovarian malignancies, in part because it tends to be resistant to platinum-based chemotherapy. At present, little is known about the molecular genetic alterati…

2010
Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma.
Science (New York, N.Y.) ·doi:10.1126/science.1196333

Ovarian clear cell carcinoma (OCCC) is an aggressive human cancer that is generally resistant to therapy. To explore the genetic origin of OCCC, we determined the exomic sequences of eight tumors after immunoaffinity purification of cancer …

2009
Frequent activating mutations of PIK3CA in ovarian clear cell carcinoma.
The American Journal of Pathology ·doi:10.2353/ajpath.2009.081000

Ovarian clear cell carcinoma (CCC) is one of the most malignant types of ovarian carcinomas, particularly at advanced stages. Unlike the more common type of ovarian cancer, high-grade serous carcinoma, ovarian CCC is often resistant to plat…