Andrey M. Cummings

No ORCID on file · 1 paper in corpus · active 1997

Study types

  • article 1
article 1997
Ketoconazole Impairs Early Pregnancy and the Decidual Cell Response via Alterations in Ovarian Function
·doi:10.1093/toxsci/40.2.238

Ketoconazole (KCZ) is an imidazole antifungal agent that also affects P450 enzymes of the mammalian steroidogenic system. Several steps in the ovarian steroidogenesis pathway are known to be inhibited by KCZ, but previous work has failed to…