Diao L

ObjectiveTo evaluate the impact of Day-3 embryo cell number on pregnancy, obstetric, and perinatal outcomes after frozen-thawed single blastocyst transfer (SBT).MethodsThis retrospective cohort study included 6437 frozen-thawed SBT cycles p…

Adenomyosis is characterized by the invasion of endometrial glands and stroma into the myometrium. Its clinical manifestations often include dysmenorrhoea, excessive menstrual bleeding and infertility. Reduced pregnancy and live birth rates…

BackgroundChronic endometritis (CE) is a persistent inflammatory condition associated with adverse pregnancy outcomes. Although impaired endometrial angiogenesis is thought to contribute to its pathogenesis, the underlying molecular mechani…

Uterine dendritic cells (uDCs) are critical for endometrial function, yet their origin and functional roles during the pre- and post-implantation periods in the human endometrium remain largely unknown. We hypothesize that distinct uDC subs…

BackgroundThin endometrium (TE) has been widely recognized as a critical cause of various obstetric and gynecological conditions. Although the role of stem cells in endometrial functions and their pathologies has been suggested, the identit…

The pathways of gametogenesis encompass elaborate cellular specialization accompanied by precise partitioning of the genome content in order to produce fully matured spermatozoa and oocytes. Transcription factors are an important class of m…