Heino TJ

ORCID: 0000-0003-2274-6834 · 1 paper in corpus

2025

Female Mice with HSD17B1 Inactivation Show Mild Hyperandrogenism without Notable Impact on Reproductive Function or Bone.

Endocrinology ·doi:10.1210/endocr/bqaf167

17β-hydroxysteroid dehydrogenase 1 (HSD17B1) is the primary enzyme responsible for the activation of estrone (E1) to estradiol (E2) in ovaries and extra-gonadal tissues of both humans and rodents. In the present study, molecular modeling id…