Scott CL

ORCID: 0000-0002-3689-5956 · 5 papers in corpus · active 2019-2025
2025
Therapeutic advances in medical oncology ·doi:10.1177/17588359251396651

Epithelial ovarian cancer (OC) comprises molecularly distinct disease types, with high-grade serous ovarian cancer (HGSOC) accounting for ~75% of OC diagnoses; ovarian clear cell carcinoma (OCCC) and endometrioid ovarian carcinoma (EnOC) at…

2024
Cancers ·doi:10.3390/cancers16244187

Despite significant advances in treatments, ovarian cancer (OC) remains one of the most prevalent and lethal gynecological cancers in women. The frequent detection at the advanced stages has contributed to low survival rates, resistance to …

2022
Frontiers in genetics ·doi:10.3389/fgene.2022.886170

High-grade serous ovarian carcinoma (HGSOC) is a genomically unstable malignancy responsible for over 70% of all deaths due to ovarian cancer. With roughly 50% of all HGSOC harboring defects in the homologous recombination (HR) DNA repair p…

2020
Gynecologic Oncology ·doi:10.1016/j.ygyno.2019.12.015

ObjectiveMucinous ovarian carcinoma (MOC) is an uncommon ovarian cancer histotype that responds poorly to conventional chemotherapy regimens. Although long overall survival outcomes can occur with early detection and optimal surgical resect…

2019
Nature communications ·doi:10.1038/s41467-019-11862-x

Mucinous ovarian carcinoma (MOC) is a unique subtype of ovarian cancer with an uncertain etiology, including whether it genuinely arises at the ovary or is metastatic disease from other organs. In addition, the molecular drivers of invasive…