Božnar P

No ORCID on file · 1 paper in corpus · active 2011

Study types

  • other 1

Condition tags

  • endometriosis 1
other 2011
Design and synthesis of substrate mimetics based on an indole scaffold: potential inhibitors of 17β-HSD type 1
Hormone molecular biology and clinical investigation ·doi:10.1515/HMBCI.2011.012

BACKGROUND: Human 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) acts at a pre-receptor level. It catalyzes NADPH-dependent reduction of the weak estrogen estrone into the most potent estrogen estradiol, which exerts its proliferative e…