Emmanouíl Karteris

preprint 2026

MicroRNA-Mediated Rewiring of the PI3K–AKT–mTOR Axis Reveals Divergent Regulatory Networks and Metabolic Vulnerabilities in Endometriosis-Associated Ovarian Cancers (EAOCs)

·doi:10.20944/preprints202607.1410.v1

Background: Endometriosis-associated ovarian cancers (EAOCs), including clear cell (OCCC) and endometrioid (EnOC) subtypes, frequently activate the PI3K/AKT/mTOR signaling axis. While genomic aberrations are well documented, the coordinate…

review 2024

The "Road" to Malignant Transformation from Endometriosis to Endometriosis-Associated Ovarian Cancers (EAOCs): An mTOR-Centred Review

Cancers ·doi:10.3390/cancers16112160

Ovarian cancer is an umbrella term covering a number of distinct subtypes. Endometrioid and clear-cell ovarian carcinoma are endometriosis-associated ovarian cancers (EAOCs) frequently arising from ectopic endometrium in the ovary. The mech…

article 2018

Differential expression of mTOR components in endometriosis and ovarian cancer: Effects of rapalogues and dual kinase inhibitors on mTORC1 and mTORC2 stoichiometry

International journal of molecular medicine ·doi:10.3892/ijmm.2018.3967

Endometriosis is a well‑known risk factor for ovarian cancer. The genetic changes that characterise endometriosis are poorly understood; however, the mechanistic target of rapamycin (mTOR) pathway is involved. In this study, we investigated…

article 2009

Congenital Imperforate Hymen with Hydrocolpos and Hydronephrosis associated with Severe Hydramnios and Increase of Maternal Ovarian Steroidogenic Enzymes

·doi:10.1016/j.jpag.2009.10.002

Study objectiveTo study clinical features of patient presented with severe hydramnios, associated with hydronephrosis, that was antenatally diagnosed and has been successfully treated immediately after birth. At a molecular level, we invest…

letter 2003

The Glu298→Asp polymorphism of the endothelial nitric oxide synthase gene is associated with endometriosis

Fertility and sterility ·doi:10.1016/s0015-0282(03)02204-0